EXPERIMENTAL BLADDER TUMOR

CD8+ T Lymphocyte Subsets in Bladder Tumor Draining Lymph Nodes

Background: Cytotoxic CD8+ T cells, as essential parts of the adaptive immune system, play pivotal roles in anti-tumor immune responses. It is well documented that cytokine expression profiles and activation status of these cells during anti-tumor immune responses affect the outcome of host-tumor interaction. Objective: To investigate the percentages of CD8+ lymphocytes and their subsets in...

Experimental Bladder Reconstruction

Giant Intradiverticular Bladder Tumor

BACKGROUND Intradiverticular bladder tumors are rare. This renders diagnosis of an intradiverticular bladder tumor difficult. Imaging plays a vital role in achieving the diagnosis, and subsequently staging of the disease. CASE REPORT A 74-year-old male presented to our center with a few months history of constitutional symptoms. Upon further history, he reported hematuria two months prior to pr...

Mouse Bladder Tumor Antigens

Table 1 Expression of antigens defined by antibodies 3872 and 6.10 in frozen sections of tumor, as detected by immunohistology A modification of the Sternberger PAP technique (6) was used to demonstrate antigen expression in frozen sections of various tissues, as described under "Materials and Methods." The degree of staining detected was graded from (negative)through + (weakly positive) to +++...

Experimental bladder carcinogenesis-rodent models.

Several rodent models of bladder cancer development have been established. The aim of this review article is to provide a critical assessment of different animal models available for the study of bladder carcinogenesis, its chemoprevention and therapy. All, except for transgenic and knockout animals, require 8-12 months experimental periods in order to generate a high yield of neoplasias. Spont...